![]() intervertebral implant with expandable bone fixation limbs
专利摘要:
INTERVERTEBRAL IMPLANT WITH EXPANDABLE BONE FIXATION MEMBERS. It is an intervertebral implant (10) configured to be fixed in an intervertebral space defined by a first and a second vertebral bodies(20). The intervertebral implant includes an implant body, sized to be inserted into an intervertebral space, and a fixation unit (22) configured to attach to the implant body. The attachment unit includes a housing (36) which defines a surface facing the first vertebral body and a surface facing the second vertebral body, separated from the first along a transverse direction. The fastening unit further includes at least one fastening member (38) carried in the carcass and movable between a retracted position and an expanded position, wherein, in the expanded position, the fastening member leaves the carcass and penetrates into one of the vertebral bodies . 公开号:BR112012005663A2 申请号:R112012005663-8 申请日:2010-09-17 公开日:2021-07-27 发明作者:Darrell C. Brett 申请人:Synthes Gmbh; IPC主号:
专利说明:
Invention Patent Descriptive Report for "IMPLANTE . INTERVERTEBRAL WITH EXPANDABLE BONE FIXATION MEMBERS” CROSS REFERENCE TO RELATED ORDERS . The present application claims the benefit of provisional United States Patent Application Serial No. 61/243,297, filed on September 17, 2009, and Provisional United States Patent Application Serial No. 61/260,364, filed with November 11, 2009, the disclosures of which are incorporated herein by reference as if set forth in full in this document. BACKGROUND OF THE INVENTION The human spinal column (also called the spinal cord or just spine) houses the spinal cord in its spinal canal. The spine is made up of several vertebrae. A common vertebra has two main parts: an anterior part, which includes the vertebral body, and a posterior part, which involves the foramen. Each vertebral body defines superior vertebral endplates and inferior H, such that two adjacent vertebrae define an intervertebral space” with disc material between the respective endplates. Historically, certain spinal anomalies required the complete removal of a disc from the intervertebral space, followed by fusion of adjacent vertebrae. This “spinal fusion” procedure, still in use today, is a widely accepted surgical treatment for symptomatic cervical and lumbar disc degenerative diseases. Older fusion procedures included introducing an implant, such as a spacer, made from the patient's hip bone or cadaver bone into the intervertebral space in order to correctly position the adjacent vertebrae until they fused together. More modern procedures use implants made from a material with a relatively low modulus of elasticity to stimulate bone growth. For example, the implant may contain parts of the patient's own bone, such as within openings of the implant. Conventional implants can be made of any desired material, including radiolucent materials such as polyether ether ketone (PEEK), ultra high molecular weight polyethylenes (UHMWPE) or polysulfones (PSU). It may be desirable for the material to have a modulus of elasticity between 3 and 5 GPa. Conventional intervertebral implant models aim to achieve fixation of the implant in the intervertebral space, SUMMARY | According to one embodiment, an intervertebral implant. is configured to be fixed in an intervertebral space defined by a first vertebral body and a second vertebral body. The intervertebral implant includes a . implant body, sized to be inserted into an intervertebral space, and a fixation unit, configured to attach to the implant body. The clamping unit includes a housing defining a surface facing the first vertebral body and a surface facing the second vertebral body, separated from the first along a transverse direction. The housing defines a channel. The clamping unit further includes a first upper clamp and a second lower clamp transversely opposite the first. Each clamp is disposed in the channel such that each includes a transom and a pair of spaced pins extending transversely outward from the transom. Each cross member defines respective first and second cam surfaces. The intervertebral implant further includes an actuator configured to travel along a distal direction within the housing. 15 substantially orthogonal to the transverse direction, The actuator is configured to engage the first and second cam surfaces at substantially the same time in order to cause the terminal ends of the pins of the first clamp BR to move in the transverse direction. BRIEF DESCRIPTION OF THE DRAWINGS The above summary, as well as the detailed description of exemplary embodiments of the present invention, will be better understood when read in conjunction with the accompanying drawings. In order to elucidate the exemplary embodiments of the present invention, reference will be made to the drawings. It should be kept in mind, however, that the present invention is not limited to the structures and instruments exactly as illustrated. In the drawings: Figure 1A is a perspective view of a pair of vertebral bodies separated by an intervertebral space; Figure 18 is a perspective view of the vertebral bodies illustrated in Figure 1 with an intervertebral implant inserted into the intervertebral space between them; Figure 2A is a perspective view of an intervertebral implant including an implant body and a fixation unit connected thereto illustrating the fixation unit according to one embodiment in a retracted position; | Figure 28 is a perspective view of the implant. intervertebral as shown in Figure 2A illustrating the fixation unit in an expanded position; . Figure 2C is an exploded view of the intervertebral implant - shown in Figure 2A illustrating the connection of the fixation unit with the implant body; Figure 2D is a top plan view of the intervertebral implant shown in Figure 2A, with parts removed for clarity; Figure 2E is an anterior plan view of the intervertebral implant shown in Figure 2A, with parts removed for clarity, shown within an intervertebral space; Figure 2F is a side view of the intervertebral implant shown in Figure 2E, with parts removed for clarity; Figure 2G is a perspective view of the fixing unit 15 shown in Figure 2B; Figure 2H is a top plan view of the intervertebral implant * as shown in Figure 2B, with parts removed for purposes of . clarity; Figure 21 is an anterior plan view of the intervertebral implant as shown in Figure 2B, with parts removed for clarity, shown within an intervertebral space; Figure 2) is a side view of the intervertebral implant as shown in Figure 21, with parts removed for clarity; Figure 3A is a top plan view of an intervertebral-implant that includes an implant body and fixation unit constructed in accordance with an alternative embodiment, with parts removed for clarity, illustrating the fixation unit in a retracted position. ; Figure 3B is an anterior plan view of the intervertebral implant as shown in Figure 3A, with parts removed for clarity, shown within an intervertebral space; Figure 3C is a side plan view of the intervertebral implant shown in Figure 3B, with parts removed for clarity; Figure 3D is a top plan view of the intervertebral implant as shown in Figure 3A, but illustrating the fixation unit in an expanded position; | Figure 3E is an anterior plan view of the implant. intervertebral as shown in the 3D figure, with parts removed for clarity, illustrated within an intervertebral space; - figure 3F is a side plan view of the intervertebral implant as shown in figure 3D, with parts removed for clarity; Figure 3G is a top plan view of an intervertebral implant similar to that shown in Figure 3D, but constructed in accordance with an alternative embodiment; Figure 4A is a top plan view of an intervertebral implant that includes an implant body and fixation unit constructed in accordance with an alternative embodiment, with parts removed for clarity, illustrating the fixation unit in a retracted position; Figure 4B is a front plan view of the implant. - 15 intervertebral represented in Figure 4A, with parts removed for clarity, illustrated within an intervertebral space; ” figure 4C is a side plan view of the implant ' intervertebral shown in Figure 4B, with parts removed for clarity; Figure 4D is a top plan view of the intervertebral implant as shown in Figure 4A, but illustrating the fixation unit in an expanded position; Figure 4E is an anterior plan view of the intervertebral implant as shown in Figure 4D, with parts removed for clarity, shown within an intervertebral space; Figure 4F is a side plan view of the intervertebral implant shown in Figure 4D, with parts removed for clarity; Figure 4G is a top plan view of an intervertebral implant similar to that shown in Figure 4D, but constructed in accordance with an alternative embodiment; Figure 5A is a top plan view of an intervertebral implant that includes an implant body and a fixation unit constructed in accordance with an alternative embodiment, with parts removed for clarity, illustrating the fixation unit in a retracted position; Fig. 58 is an anterior plan view of the intervertebral implant shown in Fig. 5A, with parts removed for clarity, shown within an intervertebral space; | Figure 5C is a side plan view of the implant - intervertebral shown in Figure 5B, with parts removed for clarity; Figure 5D is a top plan view of the implant. intervertebral as shown in figure SA, but illustrating the fixation unit in an expanded position; Figure 5E is an anterior plan view of the intervertebral implant shown in Figure 5D, with parts removed for clarity, shown within an intervertebral space; Figure 5F is a side plan view of the intervertebral implant shown in Figure 5D, with parts removed for clarity; Figure 5G is a top plan view of an intervertebral implant similar to that shown in Figure SD, but constructed in accordance with an alternative embodiment; Figure 6A is a top plan view of an implant. - 15 intervertebral including an implant body and a fixation unit constructed in accordance with an alternative embodiment, with parts removed for the sake of clarity, illustrating the fixation unit in an expanded position; . Fig. 68B is an anterior plan view of the intervertebral implant as shown in Fig. 6A shown disposed in an intervertebral space in a rearward position; Fig. 68C is a front plan view of the intervertebral implant as shown in Fig. 6B, with parts removed for clarity; Fig. 68D is a side plan view of the implant. —intervertebral as shown in figure 8C, with parts removed for clarity; Figure 6E is an anterior plan view of the intervertebral implant as shown in Figure 6A, with parts removed for clarity, illustrating the fixation unit in an expanded position; Figure 6PF is a side plan view of the intervertebral implant shown in Figure 68E, with parts removed for clarity; Figure 6G is a side plan view of an intervertebral implant puller shown in Figure 6A configured to return the fixation unit to the retracted position; Figure 8H is a top plan view of the extractor shown in Figure 6G; | Fig. 61 is a side plan view of the intervertebral implant as shown in Fig. 6A illustrating the extractor installed with the clamping unit in an expanded position, with parts removed for clarity; Figure 6J is a front plan view of the intervertebral implant as shown in Figure 61, with parts removed for clarity; Figure 6K is an anterior plan view of the intervertebral implant as shown in Figure 61 illustrating an actuator of the clamping unit and illustrating the clamping unit in a retracted position; Figure 6L is an anterior plan view of the intervertebral implant as shown in Figure 6K, but with parts removed for clarity; Fig. 68M is a side plan view of the implant. - 15 intervertebral as shown in figure 6L, with parts removed for clarity; & Figure 6N is a top plan view of the intervertebral implant as shown in Figure SM, with parts removed for clarity; Figure 7A is a top plan view of an intervertebral implant including an implant body and fixture unit constructed in accordance with an alternative embodiment, with parts removed for clarity, illustrating the fixture unit in a retracted position; Figure 7B is a front plan view of the implant. —intervertebral as shown in Figure 7A, with parts removed for clarity, arranged in an intervertebral space; Figure 7C is a side plan view of the intervertebral implant as shown in Figure 7B, with parts removed for clarity; Figure 7D is a top plan view of the intervertebral implant as shown in Figure 7A illustrating the fixation unit in an expanded position; Figure 7E is an anterior plan view of the intervertebral implant as shown in Figure 7D, with parts removed for clarity, disposed in an intervertebral space; | Figure 7F is a side plan view of the implant. intervertebral as shown in Figure 7E, with parts removed for clarity; figure 8A is a side plan view of an intervertebral implant similar to the intervertebral implant shown in figure 7A, but constructed according to an alternative embodiment, with parts removed for clarity; Figure 8B is an anterior plan view of the intervertebral implant shown in Figure 8A; Figure 9A is a top plan view of an intervertebral implant that includes an implant body and fixation unit constructed in accordance with an alternative embodiment, with parts removed for clarity, illustrating the fixation unit in a retracted position; Figure 9B is a front plan view of the implant. - 15 —intervertebral depicted in Figure 9A, with parts removed for clarity, illustrated within an intervertebral space; " Fig. 90 is an anterior plan view of the intervertebral implant shown in Fig. 9B, with parts removed for clarity, | illustrating the clamping unit in an expanded position; Figure 9D is an anterior plan view of an intervertebral implant similar to that shown in Figure 9B but illustrating a bone fixation member of the fixation unit constructed in accordance with an alternative embodiment; Figure 9E is a front plan view of the implant. —intervertebral as shown in figure 9D, illustrating the fixation unit in an expanded position; Figure 10A is a top plan view of an intervertebral implant that includes an implant body and fixation unit constructed in accordance with an alternative embodiment, with parts removed for clarity, illustrating the fixation unit in a retracted position; Figure 10B is an anterior plan view of the intervertebral implant shown in Figure 10A, with parts removed for clarity, shown within an intervertebral space and illustrating the fixation unit in a retracted position; | Figure 10C is an anterior plan view of the implant. intervertebral as shown in Figure 10B, but illustrating the fixation unit in an expanded position; - figure 11A is a top plan view of an implant —intervertebral including an implant body and fixation unit constructed in accordance with an alternative embodiment, with parts removed for clarity, illustrating the fixation unit in a rearward position; Fig. 118 is a front plan view of the intervertebral implant shown in Fig. 11A, with parts removed for clarity. illustrated within an intervertebral space and illustrating the fixation unit in a rearward position; Figure 11C is an anterior plan view of the intervertebral implant as shown in Figure 11B, but illustrating the fixation unit in an expanded position; . Fig. 11D is an anterior plan view of the intervertebral implant shown in Fig. 118B, illustrating the intervertebral implant in an "assembled position; Figure 11E is an anterior plan view of the intervertebral implant shown in Figure 11B, illustrating the intervertebral implant in a position as provided; Figure 11F is a top plan view of the intervertebral implant as shown in Figure 11E; Figure 12A is a top plan view of an intervertebral implant that includes an implant body and fixation unit constructed in accordance with an alternative embodiment, with parts removed for clarity, illustrating the fixation unit in a retracted position; Figure 12B is an anterior plan view of the intervertebral implant shown in Figure 12A, with parts removed for clarity, shown within an intervertebral space; Figure 12C is an anterior plan view of the intervertebral implant as shown in Figure 12B, but illustrating the fixation unit in an expanded position; Figure 13A is a top plan view of an intervertebral implant that includes an implant body and fixation unit constructed in accordance with an alternative embodiment, with parts removed for clarity, illustrating the fixation unit in a retracted position; | Figure 13B is an anterior plan view of the intervertebral implant as shown in Figure 13A, with parts removed for clarity, shown within an intervertebral space; Figure 130 is a side plan view of the intervertebral-implant shown in Figure 13B, with parts removed for clarity; Figure 138D is an anterior plan view of the intervertebral implant as shown in Figure 13B, illustrating the fixation unit in an expanded position; Figure 13E is a side plan view of the intervertebral implant shown in Figure 13D, with parts removed for clarity; Figure 13F is a top, schematic plan view of an intervertebral implant similar to that shown in Figure 13A, but constructed in accordance with an alternative embodiment; Figure 14A is a top plan view of an intervertebral implant - 15 that includes an implant body and a fixation unit constructed in accordance with an alternative embodiment, with parts removed for clarity, illustrating the fixation unit in a back position; Figure 14B is a front plan view of the intervertebral implant as shown in Figure 14A, with parts removed for clarity, shown within an intervertebral space; and Figure 14D is an anterior plan view of the intervertebral implant as shown in Figure 14B, illustrating the fixation unit in an expanded position. DETAILED DESCRIPTION Referring to Figures 1A and 1B, a first upper vertebral body 12a defines an upper vertebral endplate 13a of an intervertebral space 14 and an adjacent second lower vertebral body 12b defines a lower vertebral endplate 12b of the same intervertebral space 14. Thus , intervertebral space 14 forms between vertebral bodies 12a and 12b. Vertebral bodies 12a and 12b can be anatomically adjacent vertebral bodies or vertebral bodies that remained after performing a discectomy that removed a vertebral body positioned between them. As illustrated, the intervertebral space 14 is shown following a discectomy in which the disc material has been removed to prepare the intervertebral space 14 to receive an orthopedic implant, such as the intervertebral implant shown in Figure 2. Therefore, the implant 10 is configured to be inserted into the intervertebral space 14 and restore height while | keeps mobility. Intervertebral space 14 can be at any point. desired along the column. As will be appreciated from reading the description below, the implant 10 can be sized as desired to be - implanted in an intervertebral disc space in any region of the spine - including the lumbar, thoracic, cervical, sacral and coccygeal regions. We will use specific terminology in the description below for convenience only and therefore not intended to limit the scope of the invention. The words “right”, “left”, “inferior” and “upper” indicate meanings in the drawings to which we refer. The words “internal” or “distal” and “external” or “proximal” refer, respectively, to directions towards and away from the geometric center of the implant and parts of it. The words "anterior", "posterior", "superior", "inferior", "middle", "lateral" and related words or phrases indicate preferred positions and orientations in the human body to which we refer and should not be interpreted in a limiting way . The terminology includes the words listed above, . 15 its derivatives and words of the same meaning. The implant 10 and several of its components are described & in this document extending horizontally in the longitudinal “L” and lateral directions. “A” and vertically in the transverse direction “T”. Unless otherwise noted, we will use the terms “lateral”, “longitudinal”, and “transverse” to describe the orthogonal directional components of various components. The lateral A and longitudinal directions L are angularly displaced, for example substantially orthogonal, in relation to each other and in relation to the transverse direction T. It is worth mentioning that, although the longitudinal and lateral directions are shown extending in a horizontal plane and , the transverse direction, in a vertical plane, it is contemplated that the planes covering the various directions divide during use. For example, when implant 10 is implanted in an intervertebral space, such as intervertebral space 14, the transverse direction T will extend substantially vertically along the superior-inferior (or caudal-cranial) direction, whereas the plane defined by the longitudinal L and lateral A directions will be substantially in the anatomical plane defined by the anterior-posterior and mediolateral directions, respectively. Therefore, we will use the directional terms “vertical” and “horizontal” to describe the implant 10 and its components as illustrated for clarity and elucidation purposes only. Referring now to Figures 2A to 2C, the intervertebral implant 10 includes an implant body 20 and an attachment unit 22 configured to secure the implant body 20 to the first 12a and second 12b vertebral bodies within the intervertebral space 14. The implant 10 and its components | can be made from any of a variety of biocompatible materials, . such as cobalt-chrom-molybdenum (CoCrMo), titanium and titanium alloys, stainless steel, ceramics or polymers such as polyether-ether-ketone (PEEK), ultra-high-molecular-weight-polyethylenes (UHMWPE) or polysulfones ( PSU) materials —bioresorbables and allograft (eg, allograft and xenograft). It is possible to add or apply a coating to the implant 10 to improve its physical and chemical properties. Coatings can help ensure internal or external bone growth or medication. Examples of coatings include plasma sprayed titanium or hydroxyapatite coatings. The implant body 20 defines a front end 24 and a longitudinally opposite rear end 26, an upper end 28 and a transversely opposite lower end 30, in addition to opposing side sides 32 and 34. The upper 28 and lower ends 30 can be configured to to face the corresponding vertebral endplates 13a and 13b of bodies - 15 upper vertebral 12a and lower 12b, respectively. In some embodiments, the upper 28 and lower 30 ends may be configured to make contact with corresponding vertebral endplates 13a and 13b. The implant 10 can. be inserted into the intervertebral space 14 along an insertion direction which may be in an anterior-posterior approach (eg when vertebral bodies 12a and 12b are cervical vertebral bodies) in an orientation such that the anterior longitudinal end 24 is anterior to posterior longitudinal end 26. The implant body can be manufactured to the desired size and dimension and is shown substantially in a "D" shape so that the front end 24 extends substantially straight in the lateral direction A and the lateral sides 32 and 34 curve towards each other in a backwards direction towards the rear end 26. According to the illustrated embodiment, the implant body 20 defines a substantially "D"-shaped central opening 25, which extends transversely within the implant body 20 (across it as illustrated). The central opening 25 can receive any suitable material that stimulates bone growth, such as allograft and xenograft, in order to stimulate bone growth with the vertebral bodies 12A and 12B after the insertion of the implant 10 into the intervertebral space 14. The implant body 20 can be solid, as illustrated, or can define perforations that penetrate or pass through it, in which it is possible to insert, for example, the material to stimulate bone growth. | The implant body 20 defines a transverse height H between . the upper 28 and lower 30 ends. The height H may be substantially constant from the leading end 24 to the trailing end 26 or it may be variable. from the anterior end 24 to the posterior end 26 in order to impose or restore a lordotic curvature of the vertebral bodies 12a and 12b. Thus, the height H can decrease towards the rear from the front end 24 to the rear end 26, or else increase towards the rear. Furthermore, the height H can be constant or variable between lateral sides 32 and 34, if desired. In view of this, the upper 28 and lower 30 ends may be substantially flat, or else they may be curved, wavy, or any other desired shape to mate with the vertebral endplates 13a and 13b. It is also possible to supply implant kits 10, each with several implant bodies 20 of different sizes or shapes. For example, the kit may include multiple implant bodies 20 of different heights H, so that the implant bodies 20 in the kit match the heights of different intervertebral spaces along a patient's spine or the heights of intervertebral spaces of different patients. * The clamping unit 22 includes a clamping housing 36 . configured to be installed or otherwise connected to the implant body 20. The fixture housing 36 comprises, either directly or indirectly, at least one bony or vertebral fixture member 28 and at least one actuator 40, configured to move the unit clamps 22, and in particular the at least one clamping member 38 between a recessed position shown in Figure 2A and an expanded position shown in Figure 2B, in order to secure the clamping unit 22 and therefore the implant. 10 in vertebral bodies 12a and 12b. The clamp housing 36 defines a front end 42 and a longitudinally opposed rear end 44, an upper end 46 and a transversely opposed lower end 48, in addition to opposing side sides 50 and 52. The upper 46 and lower ends 48 can be configured to to face the corresponding vertebral endplates 13a and 13b of the upper 12a and lower 12b vertebral bodies, respectively. In some embodiments, the upper 46 and lower 48 ends can be configured to make contact with corresponding vertebral endplates 13a and 13b. In accordance with the illustrated embodiment, the front end 42 defines a proximal end of the fixture housing 36 and the rear end 44 defines a distal end of the fixture housing 36, spaced from the proximal end in the insertion direction along a central longitudinal axis. 37. | Attachment housing 36 and implant body 20 include . respective complementary hitch lines 54 and 56 configured as desired to engage or otherwise connect fixture housing 36 to - implant body 20. In accordance with the illustrated embodiment, hitch 54 of fixture unit 22 is configured as a transversely elongated rail 58 which protrudes laterally from sides 50 and 52 of the fixture housing 36. The rails 58 may terminate above the lower end 48 of the fixture housing 36. According to the illustrated embodiment, the hitch line The complementary 56 of the implant body 20 is configured as a pair of transversely elongated slots 60 -sized to receive the rails 58. The slots 60 may terminate above the lower end 30 of the implant body 20. The slots 60 are disposed on opposite sides of a pocket 62 defined by the body and implant 20 and sized to receive the fixation housing 36. Thus, the fixation unit 22 can connect to the - 15 color implant body 20 by inserting the fixture housing 36 into the pocket 62 of the implant body 20 so that the rails 58 are received in the slots 60. The fixture housing 36 may define a longitudinal length greater than the end. front 24 of the implant body 20, causing the fixture housing 36 to extend longitudinally into the central opening 25. The rails 58 and slots 60 can be sized so that the upper 46 and lower ends 48 of the fixture housing 36 align or substantially level with the upper 28 and lower 30 ends of the implant body 20. Hence, the upper 46 and lower 48 ends of the fixture housing 36 and the upper 28 and lower 30 ends of the implant body 20 can be configured to make —contact with vertebral endplates 13a and 13b. Alternatively, part or all of the upper 28 and lower 30 ends of the implant body 20 and/or part of or all of the upper 46 and lower ends 48 of the fixture housing may be suspended relative to the vertebral endplates 13a and 13b. Making contact with or being suspended relative to the respective vertebral endplates 13a and 13b, the upper ends 28 and 46 and lower ends 30 and 48 face in a direction with a transverse directional component so that we can say that they face the vertebral bodies 12a and 12b and therefore define surfaces facing them. As defined above, the engagement lines 54 and 56 can be configured as desired to facilitate the connection of the fixation unit 20 with the implant body 20. For example, the fixation unit 22 can be integrated with the implant body 20. | Referring also to figures 2D to 2F, the unit of . attachment 22 includes at least one opening 63 formed in attachment housing 36 which receives actuator 40, and at least one channel which receives at least one attachment member 38. According to the illustrated embodiment, the housing cleat 36 defines a first pair of laterally spaced upper channels 64 and a second pair of laterally spaced lower channels 65, which can be vertically aligned to the upper channels 64. Channels 64 and 65 may extend in any desired direction and extend in any direction. a direction with longitudinal and transverse directional components, according to the illustrated embodiment. For example, the upper channels 64 extend longitudinally and transversely upwards to define a first proximal end, which extends from the proximal end 42 of the clamp housing 36, and a second distal end, which extends to the end. upper 46. Lower channels 65 extend longitudinally and transversely downwards to define a first. 15th proximal end, extending from proximal end 42 of clamp housing 36, and a second distal end, extending to lower-end 48. The distal ends of channels 64 and 65 are therefore transverse and . longitudinally offset with respect to the respective proximal ends of channels 64 and 65. In accordance with the illustrated embodiment, channels 64 and 65 extend laterally into sides 50 and 52 of clamp housing 36, although they may be positioned in another desired manner. The clamping unit 22 may include a pair of caps 66 which attach to the sides 50 and 52 of the clamping housing 36 to cover and laterally close the channels 64 and 65. Thus, the caps 66 may include the engagement rails. 58 as defined above. The fastening member 38 may be in the form of a first clamp 68, which defines a proximal end 77 and an opposite distal or terminal end 79, which, in turn, defines corresponding spikes 73 configured to penetrate a corresponding vertebral body ( for example, through the endplate) in order to secure the fixation unit 22 and therefore the implant 10 in the vertebral body. Clamp 68 includes a bar in the form of a transom 70 at the proximal end 77 and at least a first pair of laterally spaced pins 72 that protrude from any point of the transom 70, such as from opposite outer ends of the transom 70 , as illustrated. The implant 10 may include a second fixation member in the form of a second clamp 69 which further includes a second pair of laterally spaced pins 74 that protrude from either | stitch of a second transom 71, such as from the outer ends. opposite sides of crossmember 71 as illustrated. Pins 72 and 74 connect to respective transoms 70 and 75 at - their proximal ends and define ends 73 at their distal ends, —When clamps 68 and 69 are in the recessed position, pins 72 and 74 are fully recessed in the clamping housing 36 so that the tips 73 do not extend outwardly therefrom. The tips 73 of the first 72 and second 74 pin pairs penetrate the vertebral bodies 12a and 12b as the clamping member 38 moves into the expanded position. As such, the implant 10 may include a pair of attachment members defining respective pairs of pins 72 and 74, the first pair of pins 72 defining prongs 73 at their distal or terminal ends which are configured to penetrate the first vertebral body. 12a in the expanded position, and the second pair of pins 72 defining spikes 73 configured to penetrate the second vertebral body 12b in the expanded position. . According to the illustrated embodiment, the first pair of pins 72 extends upwardly and distally in the longitudinal direction from the transom 70 within the upper channels 64, and the second pair of pins 74 extends. down and distally in the longitudinal direction from the transom 71 into the lower channels 65. It is contemplated, however, that the first 72 and second 74 pin pairs will extend from the same transom, if desired, the channels 64 and 65 can curve along its length according to a constant radius so that pins 72 and 74 are made of any suitable rigid material, or channels 64 and 65 can define different curvatures along their length. , so the pins 72 and 74 are made of any flexible material — suitable. For example, pins 72 and 74 can be made of titanium or nitinol (nickel-titanium). As described in more detail below, pins 72 and 74 move within channels 64 and 65 from the retracted position to the expanded position so that their distal ends leave the attachment housing 36 and penetrate the corresponding vertebral bodies 12a and 12b when the implant 10 is disposed in the intervertebral space 14. The distal ends of the pins 72 and 74 can leave the fixation housing 36 substantially in the transverse direction T. With continued reference to figures 2A through 2F, the actuator 40 is configured to move the at least one clamping member 38 from the retracted position to the expanded position. In accordance with the illustrated figures, the actuator 40 may be in the form of a screw 76 with external threads 78 along part or the entire length of its screw axis 89, which extend to mate. with internal threads 80 formed in opening 63. Therefore, screw 76 can be . displace distally within aperture 63 and therefore clamp housing 36 as it rotates within aperture 63 relative to clamp housing 36. During operation, screw 76 may move along one direction with a component longitudinal directional (eg, distally) from an disengaged position to an engaged position. When the bolt 76 is in the disengaged position, the clamping member 38 remains in the retracted position. When passing into the engaged position, screw 76 moves fastening member 38 to the expanded position. Referring also to Figures 2G to 2J, screw 76 defines a first engagement line, shown as a slot 82, which may extend into circumferentially or in an arc around the screw 76. The crosspieces 70 and 71 define respective openings, which may be cylindrical, that traverse them longitudinally, causing them to define respective collars 84 and 85 . 15 sized to be inserted into slot 82. Collars 84 and 85 can be sized with a circumference slightly larger than slot 82 so that screw 76 rotates relative to them. The longitudinal dimension of the collars 84 and 85' may be substantially equal to that of the groove 82, so that the collars 84 and 85 and therefore the clamps 68 and 69 are fixed substantially in the longitudinal direction to the screw 76, enabling the clamps 68 and 69 move as screw 76 rotates within opening 63. Thus, pins 72 and 74 travel distally within respective channels 64 and 65 to the expanded position as screw 76 travels, causing that the distal ends of the pins 72 and 74, and therefore the tips 73, transversely leave the fixture housing 36 at a point transversely to the outside of at least a portion of the implant body 20. The distal ends of the channels 64 and 65 may meet extend substantially in the transverse direction, so that the portions of the pins 72 and 74 leaving the channels 64 and 75, including the tips 73, are directed substantially in the transverse direction towards the interior of the respective bodies v vertebrae 12a 12b. Screw 76 defines an engagement line, shown as an inlet 86, which longitudinally penetrates the proximal end of screw 76. Inlet 86 is shown in hexagonal shape, although it may be of any suitable polygonal shape, including a "plus" shape. , in the form of “minus” or in any alternative format desired. As the inlet 86 longitudinally penetrates the screw 76, it defines a depth substantially parallel to the insertion direction of the implant 10 into the intervertebral space 14. Therefore, an anterior approach | towards the intervertebral space 14 can facilitate both the introduction of the implant 10 into the intervertebral space and the movement of the actuator 40 from the disengaged position to the engaged position, thereby similarly causing the fixation member 38 - to move from the recessed position to the expanded position. In this way, it is possible to insert an actuator tool, such as a hex wrench, into inlet 86 and turn it, either manually or automatically, in order to cause screw 76 to rotate and displace distally in relation to the clamping housing 36. In accordance with the illustrated embodiment, the proximal end of screw 76 projects longitudinally outwardly to a point proximal to the front end 42 of clamp housing 36 when screw 36 is in the disengaged position. As screw 76 travels distally to the engaged position, it travels distally to the engaged position. For example, opening 63 may culminate in a point that prevents further displacements of screw 76 after it assumes the engaged position. In accordance with the illustrated embodiment, the proximal end of screw 76 is substantially flush with front end 42 of the clamp housing when screw 76 & is in the engaged position. As screw 76 travels distally, fixation member 38 also travels distally, causing pins 72 and 74 to travel distally within their respective channels 64 and 65, thus causing tips 73 project, in principle, transversely outward from the upper 46 and lower 48 ends of the clamping housing 36, respectively. As screw 76 and pins 72 and 74 continue to travel distally, tips 73 extend farther and farther outward from clamp housing 36 until screw 76 assumes the engaged position, when the tips 73 of pins 72 and 74 are fully extended out of attachment housing 36 and into vertebral bodies 12a and 12b. If we wish to withdraw pins 72 and 74 in order to facilitate the removal of implant 10 from intervertebral space 14, we rotate screw 76 relative to fixation housing 36 in a second opposite direction, thus causing screw 76 to move approximately from the engaged position to the disengaged position. As screw 76 moves proximally, fixation member 38 also moves in the same direction, causing the tips of pins 72 and 74 to retract into respective channels 64 and 65. When screw 76 has recoiled by complete, thus assuming the disengaged position, the tips 73 —of pins 72and74are lowered in relation to vertebral bodies 12a and 12b and retract | all the way into the respective channels 64 and 65, thus making it possible to remove the implant 10 from the intervertebral space 14. i Although we have described the implant 10 in accordance with one embodiment, it is contemplated that it be constructed in accordance with any desired alternative embodiment. that has at least one fastening member configured to move between a retracted position and an expanded position, as described above. Various alternative embodiments of this type are described below, it should be borne in mind that we have included them in this document for purposes of elucidation and that other alternative embodiments are contemplated in addition to those explicitly described herein, for example, as defined in the appended claims. For example, Figures 3A to 3C illustrate the fixation unit 22 of the implant 10 according to an alternative embodiment, in which the fixation housing 36 includes a pair of laterally spaced fixation housing segments 36a and 36b connected to the lateral sides. 32 and 34 of implant body 20. Each housing segment 36a and 36b defines an opening 63 that receives an actuator À 40, illustrated as a screw 76, in the manner described above. An upper channel 64 extends centrally from opening 63 in carcass segment 36b, and a lower channel 65 extends centrally from the other opening 63 in carcass segment 36a. Each of the screws 76 can define a hole 81 that centrally penetrates its distal end, such that the proximal end of at least one first fixation member, illustrated as a first pin 72, enters the center hole 81 of the screw 76 disposed in the segment. of carcass 36b. The first pin 72 also penetrates the upper channel 64. The proximal end of at least one second fixation member, illustrated as a pin 74, penetrates the central hole 81 of the screw 76 disposed in the housing segment 36a so that the second pin penetrates. also in the lower channel 64. Referring also to figures 3D to 3F, the proximal ends of the pins 72 and 74 pivotally engage the respective screws within the holes 81 and can be connected to the screws 76 by adhesive or welding or, then they can be integrally connected to the screws. 76. As such, pins 72 and 74 engage the respective screws 76 with respect to both displacement and rotation, so that they both rotate and displace together with the respective screws 76 to which they attach. Pins 72674 enter respective channels 64 and 65, which extend upwards and downwards, respectively, and distally in the longitudinal direction, as described | above. Hence, screws 76 move as they rotate within housing 36 . in the manner described above, which causes pins 72 and 74 to rotate as they travel distally within respective channels 64 and 65. Prongs 73, therefore, + also rotate as they leave clamp housing 36. one of the pins 72 and 74 may include a cutting portion, eg drill bits 83 at its tips 73, to facilitate penetration into the vertebral bodies 12a and 12b as they rotate and move from the retracted position to the expanded position. The screws 76, channels 64 and 65 and pins 72 and 74 may extend substantially parallel to each other (in the longitudinal direction as shown in Figures 3A to 3F) or may be angularly offset relative to one another. For example, screws 76, channels 64 and 65, and therefore pins 72 and 74 may approach along one direction from their proximal ends to their distal ends, as illustrated in Figure 3G. As an alternative, channels 64 and 65 may move away along one direction from their BR 15 ends proximal to their distal ends. As an alternative, implant 10 may include a pair of screws 76 on each side 32 and 34. For example, each side 32 and 34 may include an upper screw 76, coupled to an upper stud in the manner described above, and | a lower screw 76 disposed under the upper screw and coupled to a lower pin in the manner described above so that each lateral side of the implant body 20 engages both the upper 12a and lower 12b vertebral bodies. Referring now to Figures 4A to 4C, the fixation unit 22 of the implant 10 is illustrated in accordance with an alternative embodiment, in which each of the laterally spaced fixation housing segments 36a and 36b includes an upper opening 63a and an opening. lower 63b, each receiving an actuator 40, illustrated as an upper screw 76a or a lower screw 76b, in the manner described above. The upper openings 63a and lower 63b can be laterally displaced with respect to each other by a distance at least equal to the thickness of the channels 64 and 65. Therefore, the upper channel 64 can extend from the lower opening 63b and the lower channel 65 can extend from the upper opening 63a so that the channels 64 and 65 of each housing segment 36a and 36b intersect and are longitudinally and transversely aligned without interfering with each other. The upper channels 64 extend centrally from the — lower openings 63b in the housing segments 36a and 36b, and the lower channels 65 extending centrally from the upper openings 63a in the segments of | housing 36a and 36b. The screws 76a and 76b each define a hole 81 that . it penetrates its distal end centrally. The proximal end of at least one first clamping member 38, such as a pair of first clamping members, - illustrated as a pair of first pins 72, penetrates the central hole 81 of the corresponding pair of lower screws 76b disposed in the lower apertures 63b and aligned with the upper channels 64. The first pins 72 also penetrate the upper channels 64 from the lower screws 76b. The proximal end of at least one second fixation member 38, such as a pair of second fixation members, illustrated as a pair of second pins 74, penetrates the central hole 81 of the corresponding pair of top screws 76a disposed in the top openings 63a and aligned with the lower channels 65. The second pins 74 also penetrate the lower channels 65 from the upper screws 76a. Referring also to figures 4D to 4F, the proximal ends of pins 72 and 74 pivotally engage the: 15 respective screws 76a and 76b within holes 81 and can be connected to screws 76a and 76b by adhesive or soldering or , then can be connected integrally to screws 76a and 76b. Thus, pins 72 and 74 engage the respective screws 76b and 76a in relation to both displacement and | rotation, so that they both rotate and move together with the respective screws 76b and 76a to which they connect. Pins 72 enter upper channels 64 from lower screws 76b, and pins 74 enter lower channels 65 from upper screws 76a. Both channels 64 and 65 extend from their respective openings 63b and 63a in a direction with longitudinal and transverse directional components. The proximal ends of the upper channels 64 are inferior to the proximal ends of the lower channels 65, and the distal ends of the channels uppers 64 are superior to the upper ends of the lower channels 65. For example, the distal ends of the upper channels 64 traverse the upper end of the fixture housing 36 and/or implant body 20. The distal ends of the lower channels 64 traverse the end of the attachment housing 36 and/or the implant body 20. During operation, the screws 76 move as they rotate within the housing 36 in the manner described above, which causes the pins 72 and 74 to rotate to the as they move distally within the respective channels 64 and 65. The tips 73 therefore also rotate as they leave the fixture housing 36. Each of pins 72 and 74 may include a cutting portion, eg drill bits 83 at their tips 73, in order to facilitate penetration | in vertebral bodies 12a and 12b as they rotate and move out of position. retreated to the expanded position. The pins 72, which connect to the lower screws 76b, pass through the upper channels 64 so that the tips 73 leave - transversely to the fixation housing 36 and/or the implant body 20 according to a direction with a transverse directional component and penetrate the upper vertebral body 12a when the implant 10 is disposed within the intervertebral space 14 and the pins 72 move into the expanded position. The pins 74, which connect to the upper screws 76a, traverse the lower channels 65 so that the tips 73 transversely leave the fixture housing 36 and/or the implant body 20 in a direction with a transverse directional component and penetrate in lower vertebral body 12b when implant 10 is disposed within intervertebral space 14 and pins 74 move into the expanded position. Channels 64 and 65 may extend substantially parallel to one another (in the longitudinal direction as illustrated in Figures 4A-15.4F) or may be angularly offset relative to one another. For example, channels 64 and 65 may approach along one direction from their ”" ends proximal to their distal ends, as shown in Figure 4G. As an alternative BR, channels 64 and 65 may move away along a direction from its proximal ends to its distal ends. Referring now to Figures 5A to 5G, the fixation unit 22 of the implant 10 is illustrated substantially as described in relation to Figures 4A to 4G, however, the pins 72 and 74 include external threads 87 along part or all of its length, for example, at the terminal end which protrudes transversely out of the clamping housing 36. Thus, as the pins 72 and 74 rotate towards the expanded position, the threads 87 engage the bodies. vertebral 12a and 12b. The threads 87 may have a pitch equal to or different from the pitch of the external threads 78 of the corresponding screws 76. Furthermore, pins 72 and 74 are illustrated as integrated with screws 76a and 76b. Referring now to Figures 6A to 6D, the clamping unit 22 includes a pair of clamping members 38 in the form of a first upper clamp 68 and a second lower clamp 69. The first clamp 68 includes a base in the form of a transom 70 and at least one first pair of laterally spaced pins 72 that protrude from any point of the header 70, such as from opposite outer ends of the header 70, as illustrated. The second clamp 10 may further include a second pair of laterally spaced pins 74 that protrude from any point on the base, illustrated as a | second beam 71, such as from opposite outer ends of the beam. 71 as illustrated. Clamps 68 and 69 may be disposed in respective upper 64 and lower 65 channels which may extend in any desired direction - such as the transverse direction as illustrated. It is contemplated that channels 64 and 65 are continuous, that is, in a single channel, or bifurcated and separated, as desired. The actuator 40 may be in the form of a screw 76 configured to move the clamping members 38 from the retracted position, in which the tips 73 are recessed into the clamping housing 36 and/or the implant body 20, to the expanded position, in which the tips 73 transversely leave the attachment housing 36 and/or the implant body 20. According to the illustrated embodiment, the actuator 40 may be in the form of a screw 76 with external threads 78 along part or all of its length, which engage with corresponding internal threads 80 formed in opening 63. Thus, screw 76 travels distally within opening 63 and therefore of clamping housing 36 as it rotates within opening. 63 with respect to clamping housing 36.” Screw 76 defines a beveled distal tip 88 that se . tapers transversely inward along a distal longitudinal direction. During operation, screw 76 moves from an disengaged position to an engaged position. When the bolt 76 is in the disengaged position, the clamping members 38 remain in the retracted position. As it moves into the engaged position, the bolt 76 moves the clamping members 38 into the expanded position. While the clamps 68 and 69 remain in their recessed positions, the respective transoms 70 and 71 are disposed adjacent to each other and therefore separated by a first distance, which can be substantially equal to zero so that the clamps 68 and 69 make contact with each other. The transverses 70 and 71 may be rounded in cross section or of some other shape that defines respective first 90 and second 92 cam surfaces that extend transversely inward along a distal longitudinal direction in order to form a gap between the proximal parts of headers 70 and 71 if they make contact with each other when in the rearward position. Referring also to Figures 6E and 6F, during operation the screw 76 travels along the longitudinally distal direction, causing it to engage or drive the first 90 and second 92 cam surfaces of the clamps 68 and 69, thus causing pins 72 and 74 to travel along the channel in one direction with a directional component | cross section. For example, channels 64 and 65 can guide the pins in order to displace them - substantially in a transverse direction relative to the clamp housing 36. More specifically, as the screw 76 travels distally within the . housing, chamfered tip 88 engages cam surfaces 90 and 92 of clamps 6869. As chamfered tip 88 is tapered, it forces clamps 68 and 69 transversely outward as screw 76 continues to travel distally. As such, the beveled tip 88 can be said to define a third cam surface configured to engage the first 90 and second cam surfaces 92 at substantially the same time to cause the terminal ends 73 of the pins 72 and 74 to displace each other. if in the transverse direction until the screw 76 reaches the engaged position. When bolt 76 adopts the engaged position, clamps 68 and 69 will assume their expanded positions so that pins 72 extend upwards beyond clamping housing 36 and pins 74 extend downwards beyond clamping housing 36 Thus, when the implant 10 is disposed in the intervertebral space 14, the pins 72 penetrate the upper vertebral body 12a and the pins 74 penetrate the inferior vertebral body 12b. Clamps 68 and 69, & including transoms 70 and 71 and pins 72 and 74, can be substantially rigid: or flexible, as desired. It is contemplated that tip 88 of screw 76 will be configured to force clips 68 and 69 transversely outward as screw 76 moves longitudinally distally if cam surfaces 90 and 92 are angularly displaced with respect to the direction. transverse or if the screw tip 88 is angularly displaced with respect to the transverse direction. In accordance with the illustrated embodiment, all cam surfaces 90 and 92, as well as the cam surface defined by the beveled tip 88, are angularly offset relative to the transverse direction. Cam surfaces can be substantially flat, curved, arched, or any other desired shape. Referring now also to Figs. 6G and 6H, the clamping unit 22 may further include a second actuator in the form of a puller 96 — configured to engage the crossmembers of the first 68 and second 69 clamps to cause the terminal ends. 73 of the pins 72 of the first clamp 68 retract downwardly into the clamping housing 36 and also with the terminal ends 73 of the pins 74 of the second clamp 69 retracting upwardly into the housing. Puller 96 may be in the form of a screw 98 defining an outthreaded shaft 100 along part or all of its length, which | engages internal threads 80 of opening 63 in clamping housing 36. Hence, screw 98 moves distally within aperture 63 and therefore clamping housing 36 as it rotates within aperture 63 relative to housing housing. fixation - 36. Screw 98 further defines a collar 102 at its distal end which is rotatable relative to threaded shaft 10. Collar 102 defines at least one beveled surface, such as a pair of beveled surfaces 104 and 106, which may be angularly displaced with respect to the transverse direction. In accordance with the illustrated embodiment, the chamfered surfaces 104 and 106 taper towards each other along a proximal direction opposite to the distal insertion direction of the screw98. Transmitters 70 and 71 may define respective first 108 and second 110 extraction cam surfaces configured to respectively engage chamfered surfaces 104 and 106 of extractor 96. Extraction cam surfaces 108 and 110 may be in the form of notches 112 and 114 that . 15 transversely penetrate, but do not pass through, the transverse outer surfaces of the headers 70 and 71. The notches 112 and 114 may be sized to receive respective chamfered surfaces 104 and 106. Extraction cam surfaces 108 and 110 may be angularly offset with respect to the transverse direction or may extend in any desired direction. Extraction cam surfaces 108 and 110 and chamfered surfaces 104 and 106 may be substantially flat, curved, arcuate or of some other desired shape. During operation, it is possible to remove the screw 76 after the clamps 68 and 69 assume the expanded position or otherwise leave the retracted position. Screw 98 is displaceable distally within the clamp housing 36 from an disengaged to an engaged position. While bolt 98 is in the disengaged position, clamps 68 and 69 remain in their expanded position while being actuated by bolt 76. When bolt 98 moves into the engaged position, it forces clamps 68 and 69 into the retracted position. More specifically, as screw 98 moves from the offset position to the engaged position, the chamfered surfaces 104 and 106 come into contact with the transoms 70 and 71, for example, in the notches 112 and 114, which may remain in the housing of clamping 36 while clamps 68 and 69 are in their fully expanded positions. Since collar 102 is rotational with respect to threaded screw shaft 100, chamfered surfaces 104 and 106 remain engaged with notches 112 and 114 while screw shaft 100 continues to rotate relative to | to the fixture housing 36 to displace screw 98 distally within the housing of . Attachment 36. Attachment housing 36 may define a channel for receiving collar 102 to hold bevel surfaces 104 and 106 aligned with notches 112 and 114a. As screw 98 rotates within clamping housing 36. As screw 98 travels distally, transoms 70 and 71 move along with bevel surfaces 104 and 106. Bevel surfaces 104 and 106, therefore , forces the clamps 68 and 69 to move transversely inward towards the central longitudinal axis 37. Thus, the upper clamp 68 and corresponding pins 72 travel downward until they leave the upper vertebral body 12a and recess into the carcass of fixation 36. The implant 10 can then be removed from the intervertebral space 12 or repositioned in the intervertebral space 14 as desired. Furthermore, the lower clamp 69 and corresponding pins 74 move upwards until they leave the lower vertebral body 12b and lower into the attachment housing. As such, the chamfered surfaces 104 and 106 can be called the cam surfaces, as they cause the clamping members 38 to move in a direction from the expanded position to the retracted position. - According to the illustrated embodiment, the extractor 96 can - be provided as an actuator distinct from the actuator 40. According to an alternative embodiment, the extractor 96 can be connected to the actuator 40 or form an integral part of it, so that one of the longitudinal sides of actuator 40 define distal tip 88 and the opposite longitudinal side of actuator 40 includes collar 102. Referring now to Figures 7A to 7C, clamping unit 22 may be constructed in accordance with an alternative embodiment. The clamping unit 22 may include at least one actuator 40 configured to move at least one clamping member 38 between a retracted position and an expanded position in the manner described above. The clamping unit 22 may further include a biasing member 118 operatively coupled between the actuator 40 and the clamping member 38. For example, the biasing member 118 may attach to the at least one clamping member 38 at its distal end and moving it from the retracted position to the expanded position by forces applied to it by the actuator 40. The at least one clamping member 38 may be in the form of a first upper clamping member, illustrated as a first upper clamp 68, and a second member attachment bracket, illustrated as a second lower clip 69, as described above. Thus, the first clamp 68 includes a base in the form of a transom 70 and at least one first pair of laterally spaced pins 72 that protrude from any point of the transom 70, such as the | from the opposite outer ends of the header 70 as illustrated. O . second clamp 69 may further include a second pair of laterally spaced pins 74 which protrude from any point of a base in the form of a second header 71, such as from opposite outer ends of header 71, as illustrated. Clamps 68 and 69 may be disposed in respective upper 64 and lower 65 channels which may extend in any desired direction, such as the transverse direction as illustrated. It is contemplated that channels 64 and 65 are continuous, that is, in a single channel, or bifurcated and separated, as desired. According to the illustrated embodiment, the actuator 40 may be in the form of a screw 76 with external threads 78 along part or all of the longitudinal length of its screw axis 89. The screw 76 comprises a screw head 91, which defines an outer cam surface 93, engages the distal end of screw shaft 89, and may have a lateral dimension (e.g., diameter) greater than that of screw shaft 89. Threads 78 engage internal threads 80 matings formed in opening 63 at the front end & 42 of clamping housing 36. Thus, screw 76 is displaceable distally within aperture 63 and hence clamping housing 36 as it rotates within aperture 63 relative to to the clamping housing 36. During operation, the bolt 76 moves from an disengaged to an engaged position. While the bolt 76 is in the disengaged position, the fastening members 38 remain in the retracted position. When transferred to the engaged position, screw 76 moves the fastening members 38 to the expanded position. The biasing member 118 includes a first upper flexible biasing arm 120 and a second lower flexible biasing arm 122. The arms 120 and 122 define respective proximal ends 124 and 126 extending transversely inward with respect to a pair of segments. intermediates 132 and 134 which taper transversely towards each other along the distal longitudinal direction. The proximal ends 124 and 126 attach to the attachment housing 36 at the respective attachment points 123 and 125 by means of adhesives, mechanical fasteners, friction fit, or any alternative attachment means. Arms 120 and 122 define distal ends in the form of hooks 133 which attach to transoms 70 and 71. Intermediate segments 132 and 134 connect between the proximal and distal ends of flexible arms 120 and 122. Intermediate segments 132 and 134 connect to proximal ends 124 and 126 by a hinge 127. Hooks 133 are transversely spaced apart | from each other by a distance (which can equal zero if they touch) . less than the transverse dimension of cam surface 93 of screw 76 when clamps 68 and 69 are in the withdrawn position. . Referring also to Figures 7D to 7F, the outer cam surface 93 of the screw 76 is configured to, as the screw 76 travels distally from the disengaged position to the engaged position, make contact and drive the flexible arms 120 with it. and 122 at substantially the same time. Flexible arms 120 and 122 can therefore define inner cam surfaces which engage with outer cam surface 93 of screw 76. Outer cam surface 93 defines a transverse dimension so that as it drives along with it the segments. intermediates 132 and 134, flexible arms 120 and 122 flex transversely outwardly around hinge 127, thus causing corresponding hooks and pins 72 and 74 to transversely displace outwardly within their respective channels 72 and 74 towards the expanded position, shown in Figure 7F, in which the terminal tips 73 of the pins 72 protrude upward beyond the clamping housing 36 and the terminal tips 73 of the pins 74 A project downwardly beyond the clamping housing 36 With this in mind, the inner transverse surfaces of the intermediate segments 132 and 134 can be called cam surfaces. Referring now to Figures 8A and 8B, alternatively, bias arms 120 and 122 may be substantially rigid so as not to flex in response to engagement with actuator 40. More specifically, bias arms 120 and 122 connect. pivotally to the clamping housing 36, for example, at the hinges 127. Thus, the biasing arms 120 and 122 pivot relative to the clamping housing 36 about a lateral pivot axis. The proximal ends 124 and 126 may separate from the attachment housing 36 and are disposed in the opening 63 in accordance with the illustrated embodiment. The distal ends may be in the form of hooks that connect to attachment members as described above with respect to figures 7A through 7F, or may include —integral locking pins 72 and 74, respectively. Actuator 40 may be in the form of a screw 76 with external threads 78 along part or the entire length of its screw shaft 89 which engage with corresponding internal threads 80 formed in the opening 63. Thus, the screw 76 may displace distally within aperture 63 and therefore clamp housing 36 as it rotates within aperture 63 relative to clamp housing 36. During operation, screw 76 may shift | distally from an disengaged position to an engaged position. The edge . The distal end of the screw 76 can define a cam surface 93 sized to contact the proximal ends 124 and 126 of the bias arms 120 and - 122. Thus, the proximal longitudinal surfaces of the proximal ends 1246126 have respective cam surfaces configured to receive a longitudinal biasing force that causes biasing arms 120 and 122 to pivot, which in turn causes upper clamping pins 72 and lower 74, respectively, to extend above and below the carcass 36 and penetrate into the respective upper 12a and lower 12b bodies. Referring now to Figures SA and 9B, in general terms, the clamping unit 22 may be constructed as a helix, according to an alternative embodiment. The clamping housing 36 can be positioned so that the rear end 44 aligns with the central opening 25 of the implant body 20 and the front end 42 is displaced proximally from the front end 24 of the implant body 20. The clamping unit 22 includes an actuator 40 in the form of a | hub or swivel shaft 89 which connects to the attachment housing 36 in order to rotate with respect thereto and is displaceably attached thereto. The swivel shaft 89 may or may not be threaded and may be configured to maintain a substantially fixed longitudinal position (and therefore not rotate substantially in the proximal - or distal directions) while rotating relative to the clamp housing 36. The shaft 89 defines a hitch dash, illustrated as an inlet 86, which longitudinally penetrates its proximal end. Input 86 is illustrated in hexagonal shape, although it may be of any suitable polygonal shape, including "plus" shape, "minus" shape, or any alternative shape desired in order to receive a drive member to cause the shaft rotates. The at least one clamping member 38 may include at least one pair of clamping paddles, such as a first upper clamping paddle 142 and a second lower clamping paddle 144, which pivotally engage shaft 89 in order to pivoting along with it. In accordance with the illustrated embodiment, the clamping member 38 includes a first proximal pair comprising an upper blade 142 and a lower blade 144 and a second distal pair composed of an upper blade 142 and a lower blade 144. The first pair of vanes 142 and 144 are proximal to the front end 24 of the implant body 20, and the second pair of vanes 142 and 144 are aligned with the central cavity 25 of the implant body 20. Both pairs of vanes 142 and 144 may swivelly engage shaft 89 in order to rotate with it. Blades 142 and 144 may be substantially flat in the lateral A and transverse T directions or they may be | curved, if desired, for example, if vanes 142 and 144 are displaceable with respect to axis 89 or if axis 89 is displaceable with respect to clamping housing 36. Vanes 142 and 144 may taper to form a Distal end tip 143. Each paddle 142 and 144 has a leading edge 145 and a trailing edge 146 in relation to movement from the retracted position to the expanded position. Referring also to Fig. 9C, the clamping housing 36 defines a channel, illustrated as a slot, which allows the vanes 142 and 144 to rotate from the retracted position to the expanded position. More specifically, the clamp housing 36 defines an upper blade slot 148, which receives the upper blade 142, and a lower blade slot 150, which receives the lower blade 144. Both upper 148 and lower blade slots 150 are lateral. and transversely opposite and sized so that the blades 142 and 144 rotate from a first, recessed position, in which the tips 143 are recessed transversely with respect to the vertebral bodies 12a and 12b, respectively, e.g. in the attachment housing 36, to one . 15 second expanded position, in which the points 143 transversely leave the fixation housing 36 and penetrate into the respective vertebral bodies 12a and 12b when V the implant 10 is disposed in the intervertebral space 14. For example, the slits 148 traverse both of the upper ends 46 and side 50 of the clamping housing body 36. The slits 150 pass through both the lower 48 and side 52 ends of the clamping housing 36. The first pair of slots 148 and 150 is proximal to the front end of the clamping housing 36, and the second pair of slots 148 and 150 are aligned with central cavity 25. During operation, the shaft 89 rotates from a first rotationally disengaged position, in which the clamping vanes 142 and 144 are in the lowered position, to a second rotationally engaged position, in which the vanes 142 and 144 are in the expanded position. Shaft 89 may rotate through an angle between o and 180°, such as between 20° and 90°, between the disengaged and engaged positions. Blades 142 and 144 can radially leave shaft 89 through respective blade slots 148 and 150 so that tips 143 are disposed laterally outward from intervertebral space attachment housing 14 when blades 142 and 144 are in the withdrawn position. . Clamp housing 36 includes stops at the side ends of slots 148 and 150 at upper 46 and lower ends 50 that prevent vanes 142 and 144 from rotating beyond the expanded position. As illustrated in Figures 9A through 9C, leading edges 145 and rear 146 may extend substantially straight in a direction radially outward from axis 89 toward tips 143. Alternatively, an or | both leading 145 and trailing edges 146 can be curved, as desired, in a direction radially off axis 89 towards tips 143. For example, as illustrated in Figures 9D and 9E, leading edges 145 may be curved. - concave and rear edges 146 can be convex. Alternatively, one or both of the leading 145 and trailing 146 edges may be straight, concave, convex, or curved of some other desired shape. Referring now to Figures 10A to 10C, the clamping unit 22 is constructed as described in relation to the clamping unit illustrated in Figures 9A to 9C. However, the clamping blades 142 and 144, as illustrated in Figures 10A to 10C, can be constructed by projecting radially from the axis 89 for a shorter distance than the blades 142 and 144, as illustrated in Figures 9A to 9C. Therefore, when the blades 142 and 144 are in the retracted position, they will remain within the clamp housing 36. The upper blade slots 148 may pass through the upper end 46 of the clamp housing 36, but not. 15 go through either side of the clamping housing side ends. Similarly, the slots for lower blades 150 may pass through the upper end 46 of the clamping housing 36, but not passing through any of the side ends of the clamping housing. Referring now to Figures 11A and 11B, the clamping unit 22 may include the swivel shaft 89 carried within the clamping housing 36 substantially as described above in relation to figures 9A to 9C. As such, the clamping unit 22 includes an actuator 40 in the form of a hub or swivel shaft 89 which is connected to the clamping housing 36 for the purpose of rotation with respect to it and which is displaceably secured thereto. Swivel shaft 89 may or may not be threaded and — may be configured to maintain a substantially fixed longitudinal position (and therefore not rotate substantially in the proximal or distal directions) while rotating relative to clamp housing 36. Shaft 89 defines a hitch dash, illustrated as an inlet 86, which longitudinally penetrates its proximal end. Input 86 is illustrated in hexagonal shape, although it may be of any suitable polygonal shape, including "plus" shape, "minus" shape, or any alternative shape desired in order to receive a drive member to cause the shaft rotates. Shaft 89 defines an outer circumferential surface 141 and at least one groove 147 which extends radially inwardly from the circumferential surface 141 and receives at least one attachment member 38, such as a pair of attachment members 38. axis 89 can define a pair of grooves | lengthwise apart. Slot 147 may extend around part or around . the entire circumference of shaft 89, or may include a pair of distinct grooves, each of which receives a pair of clamping members 38. The at least one clamping member 38 may include a first upper clamp 68 and a second lower clamp 69 coupled to shaft 89 in first proximal slot 147 and a first upper clamp 68 and first lower clamp 69 coupled to shaft 89 in second distal slot 147. Clamps 68 and 69 may leave shaft 89 and enter respective upper channels 64 and lower 65 which penetrate or pass through the fastening housing 36. The first clamp 68 includes a base in the form of a strut 70 and at least one first pair of laterally spaced pins 72 that protrude from any point of the strut 70, such as from opposite outer ends of transom 70 as illustrated. The second clamp 10 may further include a second pair of laterally spaced pins 74 that protrude from any point on the base. 15 is illustrated as a second transom 71, such as from opposite outer ends of transom 71 as illustrated. Clamps 68 and 69 may be disposed in respective upper 64 and lower 65 channels which may extend in any desired direction, such as the transverse direction as illustrated. It is contemplated that channels 64 and 65 are continuous, that is, in a single channel, or bifurcated and separated, as desired. Clamps 68 and 69 may define end points 73, which may be rigid and extend tangentially off axis 89 and into respective channels 64 and 65. At least part of the proximal portion of clamps 68 and 69 may be flexible to in order to bypass axis 89 when clamps 68 and 69 are in the retracted position and tangentially leave axis 89—when clamps 68 and 69 assume the expanded position. Referring also to Fig. 11C, during operation, the shaft 89 rotates from a first rotational disengaged position, in which the clamping paddles 68 and 69 are in the lowered position, to a second rotational engaged position, in which the paddles 68 and 69 move to the expanded position. Clamps 68 and 69 move within their respective channels 64 as they move from the retracted position to the expanded position. When the clamps 68 and 69 are in the withdrawn position, the tips 63 are disposed within the housing 36 and do not penetrate the respective vertebral bodies 12a and 12b. When clamps 68 and 69 assume the expanded position, tips 63 transversely leave the carcass-detachment36 and enter vertebral bodies 12a and 12b. The clamping housing 36 | may include any suitable stop that prevents shaft 89 from rotating beyond the .: engaged position. Referring now to figures 11D through 11F, the tips 73 . of the clamps 68 and 69 may be flexible and may be disposed substantially completely within the slot 147 of the shaft 89 when the shaft 89 is in the disengaged position and the clamps 68 and 69 are in the corresponding recessed position. In this way, when shaft 89 rotates from the disengaged position to the engaged position, the tips 73 penetrate the respective channels 64 and 65 until the shaft 89 adopts the engaged position, which causes the clamps 68 and 69 to move into the expanded position, such that the tips 73 leave the attachment housing 36 and penetrate adjacent vertebral bodies 12a and 12b. With reference to Figures 12A to 12C, clamping unit 22 may be constructed substantially as described above with reference to Figures 11A to 11C, however, shaft 89 may include gear teeth 152 which are longitudinally elongated and circumferentially spaced apart about of the outer circumference 141 of the shaft 89. The clamps 68 may include a complementary rack 154 with teeth 156 configured to mate with the gear teeth 152 of the shaft 89 as it rotates to drive the ends 73' towards the vertebral bodies. 12a and 12b in the manner described above. Rack 154 can be flexible, and ends 73 can be flexible or rigid, as desired. It is contemplated that it will be possible to rotate the shaft 89 in the opposite direction, from the engaged to the disengaged position, in order to cause the clamps 68 and 69 to retract from the expanded position to the retracted position. Referring now to Figures 13A to 13C, the attachment unit 22 of the implant 10 is illustrated in accordance with an alternative embodiment, in which the attachment housing 36 includes a pair of laterally spaced attachment housing segments 36a and 36b connected to the sides. sides 32 and 34 of implant body 20. Each housing segment 36a and 36b defines an opening 63 that receives an actuator 40, illustrated as a shaft 89, in the manner described above. worm thread 155 with a corresponding helical gear tooth 157 extending longitudinally about the circumference 141 of the axis 89. The clamping unit 22 may further include at least one clamping member 38, illustrated as a first upper pin 72 with a tip 73 — facing transversely downwards and a second lower pin 74 with a point 73 facing transversely upwards. Each of pins 72 and 74 may include a tooth | of helical gear 158 configured to mate with the gear teeth 157 of the respective shafts 89. The pins 72 and 74 are respectively disposed in a corresponding first upper channel 64 and a corresponding second lower channel 65 - extending in the transverse direction. inside the clamping housing 36. During operation, the shaft 89 can be disposed in a first disengaged position, in which the spikes 73 are recessed into the clamping housing 36 and therefore do not penetrate into adjacent vertebral bodies 12a and 12b when the implant is disposed in the intervertebral space 10. Referring to Figures 13D and 13E, the shaft 89 can be rotated to the engaged position, which causes the worm gear 155 to drive the gear tooth 158, thus doing that the pins 72 and 74 transversely move upwards and downwards, respectively, until the tips 73 penetrate the respective vertebral bodies 12a and 12b. Tips 73 may include drill bits and/or may be threaded, as desired, in the manner described above to secure attachment to vertebral bodies 12a and 12b. As shown in Figure 13A, the shafts 89 may extend "substantially parallel to one another in the respective clamp housing segments 36a and 36b. Alternatively, as illustrated in Fig. 13F, the axes 89 may be angularly offset relative to one another. For example, the axes of channels 89 may approach along one direction from their proximal ends to their distal ends, as illustrated in Figure 3F. As an alternative, the axes 89 may move away along one direction from their ends proximal to their distal ends. Referring now to Figures 14A and 14B, clamping unit 22 may include pivot shaft 89 carried within clamping housing 36 substantially as described above in connection with Figures 11A to 11C. As such, the clamping unit 22 includes an actuator 40 in the form of a hub or swivel shaft 89 which is connected to the clamping housing 36 for the purpose of rotation with respect to it and which is displaceably secured thereto. Swivel shaft 89 may or may not be threaded and — may be configured to maintain a substantially fixed longitudinal position (and therefore not rotate substantially in the proximal or distal directions) while rotating relative to clamp housing 36. Shaft 89 defines a hitch dash, illustrated as an inlet 86, which longitudinally penetrates its proximal end. Entry 86 is illustrated in hexagonal format, although it may be of any suitable polygonal format, including "plus" shaped, "minus" shaped, or any | desired alternative format in order to receive a trigger member to do . with the shaft to rotate. Shaft 89 may define a proximal surface 160 and a distal surface 162, plus at least one hole therethrough longitudinally between proximal 160 and distal surfaces 162. Shaft 89 may include a first upper orifice 164a and a second lower orifice 164b which passes through it at a point offset by 180° from the first hole 164a. The clamping unit 22 may include at least one clamping member 38 in the form of a first upper clamp 68 and a second lower clamp 69. The first clamp 68 includes a base in the form of a transom 70 and at least one first pair of pins laterally spaced 72 protruding from any point of the transom 70, such as from the opposite outer ends of the transom 70, as illustrated. Second clamp 10 may further include a second pair of laterally spaced pins 74 protruding from from any point on the base, illustrated as a second cross member 71, . 15 such as from opposite outer ends of transom 71 as illustrated. The headers 70 and 71 of the clamps 68 and 69 can longitudinally traverse the first holes 164a and second 164b, respectively. The headers 79 and 71 may be loosely received in the first holes 164a and second 164b, enabling them to rotate within them. , clamps 68 and 69 and associated pins 72 and 74 can pivot with respect to axis 89 around a longitudinal pivot axis defined by transoms 70 and 71, respectively. protrude to axis 89 at a point spaced inwardly from the outer circumference 141 of axis 89. Pins 72 and 74 protrude beyond transoms 70 and 71 and axis 89 along a direction substantially transverse to respective upper channels 64 and below 65. Pins 72 and 74 may be flexible or rigid, as desired, and may extend along adjacent proximal and distal surfaces of the shaft to secure clamps 68 and 69 with respect to displacement at relation to axle 89 Referring also to Fig. 14C, during operation, axle 89 rotates from a first rotational disengaged position, in which clamping paddles 68 and 69 are in the lowered position, to a second rotational engaged position, in the which blades 68 and 69 move into the expanded position. Clamps 68 and 69 move within their respective channels 64 as they move from the retracted position to the expanded position. As shaft 89 rotates in | around a longitudinal axis from the disengaged position to the engaged position, pins 72 . and 74 pivot about a longitudinal axis so as to remain oriented substantially in the transverse direction as the spikes 73 protrude towards . outside the attachment housing 36 and penetrate into adjacent vertebral bodies 12a and 12b. When the clamps 68 and 69 are in the withdrawn position, the tips 63 are disposed within the housing 36 and do not penetrate the respective vertebral bodies 12a and 12b. Clamping housing 36 may include any suitable stop that prevents shaft 89 from rotating beyond the engaged position. It is contemplated that it is possible to rotate shaft 89 in the opposite direction, from the engaged to disengaged position, in order to cause clamps 68 and 69 to retract from the expanded position to the retracted position. It should be noted that, unless otherwise specified, the term “or” is used in its non-exclusive form (eg, “A or B' includes A, BA and B or any combination of these, but need not include all of these possibilities). It should also be noted that, unless otherwise specified, the : 15 term “and/or” is used in the same way (eg, “A and/or B” includes A, B/A and B or any combination thereof, but it does not need to include all of these possibilities.) % It is worth noting that, unless otherwise specified, the verb “to include” means 'to understand' (for example, a device that includes or comprises A and B contains A and B, but how option, may contain C or additional components in addition to A and B). It is worth noting that, unless otherwise indicated, the singular forms "a", "an", "o" and "a refer to one or more than one , unless the context clearly indicates otherwise. While we have described the invention with reference to preferred embodiments or preferred methods, it is to be understood that we have adopted the words used herein for purposes of description and elucidation rather than with the intention of limiting the scope of the invention. For example, it is contemplated that, while we have described the intervertebral implant herein as configured to attach to adjacent vertebral bodies, it may alternatively be inserted into a space between any bones or bone segments (e.g. a fractured bone) as desired and then attached to adjacent bones or bone segments in the manner described in this document. Furthermore, while we have described the present invention in this document with reference to specific structures, methods and embodiments, it is not limited to the particulars disclosed herein as it extends to all structures, methods and uses within its scope. Unless otherwise stated, the structure and characteristics of various embodiments described in this document | can be further incorporated into other embodiments also described. in this document, as desired. Therefore, those skilled in the art will appreciate that the present invention is intended to cover all modifications and alternative arrangements included within its scope and essence, for example, as defined in the appended claims. |
权利要求:
Claims (52) [1] 1. Intervertebral implant configured to be secured in an intervertebral space defined by a first and a second vertebral body, the intervertebral implant being characterized as comprising: an implant body sized to be inserted into an intervertebral space; and an attachment unit configured to attach to the implant body, the attachment unit including: a housing defining a surface facing the first vertebral body and a surface facing the second vertebral body, separated from the first along a direction transverse; a first upper clamp and a second lower clamp transversely opposite the first, each clamp carried by the shell so that each includes a transom and a pair of spaced apart pins extending transversely outwardly of the transom, each transom defining respective surfaces of first and second cam; and an actuator configured to travel along a distal direction within the housing which is substantially orthogonal to the transverse direction, the actuator being configured to drive the first and second cam surfaces at substantially the same time in order to cause the terminal ends of the pins of the first clamp move in the transverse direction. [2] 2. Intervertebral implant according to claim 1, characterized in that the actuator comprises at least a third cam surface and in that at least one of the cam surfaces extends in a direction angularly displaced with respect to the transverse direction. [3] 3. Intervertebral implant according to claim 1, characterized in that the pins are substantially rigid. [4] 4. Intervertebral implant according to claim 1, characterized in that the crossmembers of the first and second clamps define the first and second cam surfaces, respectively. [5] 5. Intervertebral implant according to claim 4, characterized in that the engagement of the actuator to the first and second cam surfaces causes the terminal ends of the pins of the first clamp to project upwards beyond the housing and also causes causing the terminal ends of the pins of the second clamp to protrude down beyond the housing. [6] 6. Intervertebral implant according to claim 5, characterized in that the actuator comprises at least one third cam surface configured to engage the first and second cam surfaces and in that the third cam surface consists of at least one chamfered surface extending in a direction angularly offset with respect to the transverse direction. [7] 7. Intervertebral implant according to claim 6, characterized in that chamfered surfaces are arranged at the terminal end of the actuator. [8] 8. Intervertebral implant according to claim 7, characterized in that the beveled surfaces taper towards each other along the distal direction. [9] 9. Intervertebral implant according to claim 8, characterized in that the actuator comprises a screw with a threaded shaft that screws into the frame so that its rotation relative to the frame causes it to move within it so to engage the first and second cam surfaces. [10] The intervertebral implant of claim 4, further comprising a second actuator configured to engage the crossmembers of the first and second clamps to cause the terminal ends of the pins of the first clamp to recede downwardly into the the housing and also causing the terminal ends of the pins of the second clamp to retract upwards into the housing. [11] 11. Intervertebral implant according to claim 10, characterized in that the second actuator comprises at least a third cam surface that extends in a direction angularly displaced with respect to the transverse direction. [12] 12. Intervertebral implant according to claim 11, characterized in that the third cam surface is disposed at the terminal end of the second actuator. [13] 13. Intervertebral implant according to claim 12, characterized in that the third cam surface tapers along a proximal direction opposite to the distal direction. [14] 14. Intervertebral implant, according to claim 1, characterized in that the carcass is an integral part of the implant body. [15] 15. Intervertebral implant configured to be secured in an intervertebral space defined by a first and second vertebral body, the intervertebral implant being characterized as comprising: an implant body sized to be inserted into an intervertebral space; and an attachment unit configured to attach to the implant body, the attachment unit including: a housing defining a surface facing the first vertebral body and a surface facing the second vertebral body, separated from the first along a direction transverse, the carcass defining a channel; a first upper attachment member and a second lower attachment member transversely opposite the first, each attachment member disposed within the channel such that the second is transversely opposite the first; a biasing member comprising first and second cam surfaces that operatively engage the first and second fastening members, respectively; and an actuator configured to travel along a distal direction within the housing in accordance with a longitudinal direction substantially orthogonal to the transverse direction, the actuator being configured to engage substantially at the same time with the first and second cam surfaces in order to effect with the biasing member moving the first and second fastening members from a retracted position to an expanded position, in which an end end of the first fastening member protrudes upward beyond the housing and an end end of the second fastening member designs it separates low in addition to the housing. [16] 16. Intervertebral implant according to claim 15, characterized in that the biasing member connects to the housing at a connection point so that the first and second cam surfaces are distal to the connection point. [17] 17. Intervertebral implant according to claim 15, characterized in that the propensity member comprises a pair of arms that attach to the carcass and define the first and second cam surfaces, respectively, in which the arms flex transversely outward as the actuator engages the first and second cam surfaces. [18] 18. Intervertebral implant according to claim 15, characterized in that the propensity member comprises a pair of arms that pivotally couple to the carcass and define the first and second cam surfaces, respectively, in which the arms pivot outward as the actuator engages the first and second cam surfaces. [19] 19. Intervertebral implant according to claim 15, characterized in that each of the fixation members comprises a clamp comprising a base and a pair of spaced apart pins extending transversely outward from the base and in that the propensity member attaches to the base of each clamp. [20] 20. Intervertebral implant, according to claim 15, characterized in that the carcass is an integral part of the implant body. [21] 21. Intervertebral implant configured to be secured in an intervertebral space defined by a first and second vertebral body, the intervertebral implant being characterized as comprising: an implant body sized to be inserted into an intervertebral space; and an attachment unit configured to be supported by the implant body, the attachment unit including: a housing defining a surface facing the first vertebral body and a surface facing the second vertebral body, separated from the first along a transverse direction , and a proximal end and an opposite distal end spaced from the proximal end along a longitudinal direction angularly displaced with respect to the transverse direction; at least one attachment member extended along a central axis, the at least one attachment member being carried by the housing and movable, along a direction with a longitudinal directional component, from a retracted position to an expanded position, wherein, in the expanded position, the at least one attachment member leaves at least one surface facing the vertebrae body; and at least one actuator carried by the housing and configured to translate along a longitudinal direction so as to move the at least one attachment member from the retracted position to the expanded position, wherein the at least one attachment member is coupled to the respective one of the atlases. at least one actuator, the at least one clamping member being configured to rotate relative to the central axis as the respective one of the at least one actuator translates along a longitudinal direction. [22] 22. Fixture implant according to claim 21, characterized in that the housing defines a channel extending along one direction with both transverse and longitudinal directional components and in that the at least one member of fixation moves within the channel from the position —retracted to the expanded position. [23] 23. Intervertebral implant according to claim 22, characterized in that the canal is curved. [24] 24. Intervertebral implant according to claim 21, characterized in that the at least one fixation member is flexible. [25] 25. Intervertebral implant according to claim 21, characterized in that, when the at least one fixation member is in the expanded position, one of its terminal ends leaves the carcass in a substantially transverse direction. [26] 26. Intervertebral implant according to claim 21, characterized by the fact that at least one attachment member is fully recessed into the housing in the recessed position. [27] 27. Intervertebral implant according to claim 21, characterized in that the at least one actuator comprises a screw that is screwed to the frame and rotates with respect to it in order to move the at least one member - fixing the withdrawn position to the expanded position. [28] 28. Intervertebral implant according to claim 27, characterized in that the screw travels longitudinally in relation to the housing when rotated in relation to it. [29] 29. Intervertebral implant according to claim 27, characterized in that the at least one fixation member comprises a pair of fixation members, each of which defines a first terminal end, which penetrates into the first vertebral body, and a second terminal end, which penetrates the second vertebral body when the pair of attachment members are in the expanded position. [30] 30. Intervertebral implant according to claim 27, characterized in that the at least one fixation member defines a proximal end that is fixed to the screw, with respect to displacement in relation to it, and rotates in relation to he. [31] 31. Intervertebral implant according to claim 27, characterized in that the at least one fixation member pivotally engages the screw in order to rotate with it. [32] 32. Intervertebral implant according to claim 31, characterized in that the at least one fixation member defines a proximal end, which is rotatably fixed to the screw in order to rotate as it rotates, and one end distal end, comprising a cutting portion that rotates as the at least one attachment member moves from the retracted to the expanded position. [33] 33. Intervertebral implant according to claim 31, characterized in that the at least one fixation member defines a proximal end, which is rotatably fixed to the screw in order to rotate as it rotates, and one end distal end, which is threaded and rotates within the respective vertebral body as the at least one attachment member moves from the retracted position to the expanded position. [34] 34. Intervertebral implant according to claim 31, characterized in that the screw defines a central hole that extends into one of its terminal ends and in that the at least one fixation member connects to the screw inside the center hole. [35] 35. Intervertebral implant according to claim 27, characterized in that the at least one actuator comprises an upper screw and a lower screw, in that the at least one fixation member - comprises a first fixation member, coupled to the upper screw, and a second fixation member, coupled to the lower screw, and in that the first fixation member is configured to penetrate the first vertebral body and the second fixation member is configured to penetrate the second vertebral body when the fastening members assume the expanded position. [36] 36. Intervertebral implant according to claim 21, characterized in that the carcass is an integral part of the implant body. [37] 37. Intervertebral implant configured to be fixed in an intervertebral space defined by a first and a second vertebral body, the intervertebral implant being characterized by comprising: an implant body sized to be inserted into an intervertebral space; and an attachment unit configured to attach to the implant body, the attachment unit including: a housing defining a surface facing the first vertebral body and a surface facing the second vertebral body, separated from the first along a direction transverse; an actuator supported by the housing and which rotates relative to it so as to remain fixed, with respect to displacement relative to the housing, as it rotates relative to it. at least one clamping member with a flexible portion substantially surrounding part of a circumference of the actuator, wherein the clamping member moves from a retracted position to an expanded position in one direction with a transverse directional component that is tangential to rotation of the actuator, the clamping member having an end end configured to protrude transversely beyond one of the vertebral bodies facing surfaces of the housing when the clamping member assumes the expanded position. [38] 38. Attachment implant, according to claim 37, characterized in that the housing defines a channel that receives part of the attachment member as it moves from the retracted position to the expanded position. [39] 39. Attachment implant according to claim 38, characterized in that the channel causes the terminal end of the attachment member to move in the transverse direction when it moves from the recessed position to the expanded position. [40] 40. Intervertebral implant according to claim 37, characterized in that the flexible part comprises the terminal end. [41] 41. Intervertebral implant according to claim 37, characterized in that the terminal end is substantially rigid. [42] 42. Intervertebral implant according to claim 37, characterized in that the actuator comprises a gear with gear teeth and in that the fixation member comprises a rack that coincides with the gear teeth. [43] 43. Intervertebral implant according to claim 37, characterized in that the housing defines a proximal end and an opposite distal end away from the proximal end along a longitudinal direction substantially perpendicular to the transverse direction, wherein the actuator rotates to the along a substantially longitudinal axis. [44] 44. Intervertebral implant according to claim 37, characterized in that the at least one fixation member comprises a pair of opposing fixation members with flexible parts that substantially surround opposite parts of the circumference of the actuator. [45] 45. Intervertebral implant according to claim 37, characterized in that the carcass is an integral part of the implant body. [46] 46. Intervertebral implant configured to be secured in an intervertebral space defined by a first and second vertebral body, the intervertebral implant being characterized as comprising: an implant body sized to be inserted into an intervertebral space; and an attachment unit configured to attach to the implant body, the attachment unit including: a housing defining a surface facing the first vertebral body and a surface facing the second vertebral body, separated from the first along a direction transverse; an actuator pivotally supported by the housing so as to remain fixed with respect to displacement relative to the housing as it rotates relative to it from an disengaged to an engaged position; and at least one clamping member pivotally connected to the actuator so as to move from a retracted position to an expanded position as the actuator rotates from the disengaged position to the engaged position, in which the clamping member pivots in relative to the actuator and moves relative to the housing along one direction with a transverse directional component as the clamping member moves from the retracted position to the expanded position. [47] 47. Intervertebral implant according to claim 46, characterized in that the fixation member is substantially rigid. [48] 48. Intervertebral implant according to claim 46, characterized in that the housing defines a proximal end and an opposite distal end away from the proximal end along a longitudinal direction substantially perpendicular to the transverse direction, wherein the actuator rotates to the along a substantially longitudinal axis. [49] 49. Intervertebral implant according to claim 46, characterized in that the fixation member is fixed with regard to displacement in relation to the actuator. [50] 50. Intervertebral implant according to claim 46, characterized in that the attachment member connects to the actuator at a point spaced inwardly with respect to an outer circumference of the actuator. [51] 51. Intervertebral implant according to claim 46, characterized in that the at least one fixation member comprises a pair of opposite fixation members with flexible parts that substantially surround opposite parts of an outer circumference of the actuator. [52] 52. Intervertebral implant, according to claim 46, characterized in that the carcass is an integral part of the implant body. YEAR "DER P E : Fig1A in the CI) EE only NA 1 and FigB | LE. < the RE mo ig.2B * 3/38 | ss 46 36 = | 54 So 22 of PZ 64, 58 KO 66 42 A Aa | 40 healthy MNA SS | | er is | Ni. 25 6 7 ja 1 52 L 20 y Cs 2s | $ <A O 60 34 56 / only 30 24 Fig2C
类似技术:
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同族专利:
公开号 | 公开日 US9463091B2|2016-10-11| CN105326585A|2016-02-17| US20170095350A1|2017-04-06| JP2013505073A|2013-02-14| HK1220890A1|2017-05-19| US9737412B2|2017-08-22| CN102596109A|2012-07-18| US8617245B2|2013-12-31| US20180064554A1|2018-03-08| US8932359B2|2015-01-13| US20140052262A1|2014-02-20| ES2659063T3|2018-03-13| JP5699353B2|2015-04-08| JP2015077467A|2015-04-23| EP2477579B1|2015-12-23| CN102596109B|2015-10-21| CN105326585B|2018-12-11| WO2011035126A1|2011-03-24| US20150127109A1|2015-05-07| KR101805935B1|2017-12-06| US20110178599A1|2011-07-21| CA2773723A1|2011-03-24| CA2773723C|2017-10-31| EP2477579A1|2012-07-25| EP3011934A1|2016-04-27| JP5947923B2|2016-07-06| EP3011934B1|2017-12-13| KR20120081141A|2012-07-18|
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法律状态:
2021-08-10| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]| 2021-08-10| B08F| Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]|Free format text: REFERENTE AS 9A, 10A E 11A ANUIDADES. | 2021-09-21| B25A| Requested transfer of rights approved|Owner name: EXPANDING CONCEPTS, LLC (US) | 2021-10-13| B25A| Requested transfer of rights approved|Owner name: LDR HOLDING CORPORATION (US) | 2021-11-30| B08K| Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]|Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2640 DE 10-08-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |
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申请号 | 申请日 | 专利标题 US24329709P| true| 2009-09-17|2009-09-17| US61243297|2009-09-17| US26036409P| true| 2009-11-11|2009-11-11| US61260364|2009-11-11| PCT/US2010/049287|WO2011035126A1|2009-09-17|2010-09-17|Intervertebral implant having extendable bone fixation members| 相关专利
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